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  1. Home
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  3. An Open Quantum systems approach to Proton tunneling in DNA
Quantum Computing

An Open Quantum systems approach to Proton tunneling in DNA

Posted on May 4, 2026 by Drakshi4 min read

Innovative Quantum Circuit “Follows” Protons to Reveal Chemistry and Biology Secrets

An open quantum systems approach to proton tunneling in DNA

Researchers have created a superconducting quantum circuit that mimics the “tunneling” behavior of protons, marking a significant breakthrough for the domains of quantum physics and molecular biology. The University of California, Santa Barbara, Google Quantum AI, and Yale University collaborated to create this novel gadget, which offers a highly controlled platform for studying a phenomena fundamental to life itself. The simulator enables researchers to “follow” protons in real time by replicating their subatomic trajectories, resolving previously unidentified minor quantum effects.

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Understanding Quantum Tunneling

Through a process known as quantum tunneling, subatomic particles like protons and electrons may traverse energy barriers that, in theory, are insufficient for them to do so according to conventional physics. This process is common in nature and may be found in anything from the creation of human DNA to the process of photosynthesis, despite the fact that it could appear like a lab oddity. For example, this tunneling mechanism allows protons to move between multiple places inside a base pair in the double helix of DNA.

Because these responses are affected by intricate structural elements like barrier height and asymmetry, understanding them has historically proven to be extremely challenging. It is sometimes costly, time-consuming, and technically difficult to modify one particular variable in conventional chemical and biological research without unintentionally altering numerous others. Because of this, a lot of research on protonation has up until now had to depend on different kinds of approximation.

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A “Clean and Controllable” Model

The study team, coordinated by specialists from Michel Devoret and Victor Batista’s labs at Yale, created a device that functions as a specialized quantum simulator for proton transfer to get beyond these obstacles. The apparatus is said to be so “clean” and accurate that it can resolve extremely minor effects that the researchers had not previously predicted.

The system’s barrier height and asymmetry may be manually adjusted by users as it is constructed utilizing superconducting quantum circuits. Without the noise and interference present in natural chemical systems, this degree of control allows scientists to investigate issues like tunneling in DNA in a more clearer manner. Parking the protons in the right place is essential to having an accurate description of a chemical system, said Victor Batista, Yale’s John Gamble Kirkwood Professor of Chemistry.

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Unexpected Technical Findings

Two novel pathways in the quantum proton transfer process have already been identified by the study. First, the researchers found that protonation activation rates fluctuate greatly in an oscillating pattern rather than following a straightforward linear route. Second, the researchers discovered that the entire tunneling process may be drastically slowed down by even a little imbalance between the circuit’s barriers.

These results are important because they raise the possibility that these complex dynamics were overlooked in earlier chemical reaction models. More precise modeling of reactions in a wide range of scientific fields, including as inorganic chemistry, catalysis, and chemical biology, would probably result from better understanding of these processes.

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The Influence of Multidisciplinary Cooperation

The initiative demonstrates how multidisciplinary research is becoming more and more popular in the current period. Victor Batista, a chemist who has spent decades researching proton transfer, and Michel Devoret, a Nobel Prize winner in physics and top scientist at Google Quantum AI, were among the team’s varied members. Alejandro Cros Carrillo de Albornoz, Max Schäfer (now at UC Santa Barbara), and co-first authors Rodrigo Cortiñas (now at Google Quantum AI) were other important contributors.

The U.S. Army Research Office provided funding and the Yale Quantum Institute provided assistance for the partnership. The researchers have demonstrated that platforms built using superconducting circuits may be utilized to address important concerns in the life sciences by applying quantum computing technology to chemistry-specific problems.

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Future Consequences: From Solar Energy to Medicines

Protons can be tracked while on the way, which might help researchers with a number of useful applications. Proton transfer is essential to energy conversion and molecule stability, hence this discovery may result in the creation of:

  • New Solar Fuels: Increasing the effectiveness of light energy collection and storage.
  • Creating medications that more accurately interact with biological structures like DNA is known as advanced pharmaceuticals.
  • Specialized Materials: Developing novel materials with distinctive qualities via a deeper comprehension of their subatomic structures.

The researchers have created a new window into the subatomic realm by creating a tool that so closely resembles the structures seen in chemistry and biology. Alejandro Cros Carrillo de Albornoz pointed out that this experiment shows how contemporary quantum platforms are being utilized to investigate issues of great significance in the natural world.

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Tags

Google Quantum AIProton Tunnelingproton tunneling DNAQuantum circuit simulatorsuperconducting quantum circuitsUniversity of CaliforniaYale University

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Drakshi

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