To promote quantum, artificial intelligence, and biotechnology, NIST invests $3.19 million in small business innovation.

SBIR program news today

The National Institute of Standards and Technology (NIST) has awarded eight small enterprises more than £2.5 million in funding to promote high-tech prototyping. Critical industries such as artificial intelligence, medical diagnostics, and quantum technology are the focus of this program, which is a component of the Small Business Innovation Research (SBIR) program. During the two years allotted by these Phase II funds, businesses can turn their original ideas into working prototypes. Projects supported include quantum light sources with improved scalability, cybersecurity assessment tools, and new imaging systems. To bridge commercial feasibility, the U.S. Department of Commerce funds this study. They improve energy efficiency, public health, and national security through private innovation.

By transforming successful Phase I concepts into working prototypes, the competitively chosen projects hope to open the door for potential commercialization and the move to Phase III funding from non-SBIR sources.

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Biopharmaceutical and medical imaging standardization

Much of the funding is allocated to biotechnology and healthcare, where uniformity and accuracy are critical. To address the issue of medical imaging accuracy, Madison, Wisconsin-based Calimetrix LLC was given $399,998. For the purpose of simulating fatty liver tissue, the business is creating “phantoms,” imaging test items that resemble human anatomy. By using these phantoms, researchers and physicians may standardize comparisons of MRI and CT scans across various vendor platforms, guaranteeing that patient data is consistent, independent of the location of a scan.

Applied Imaging Solutions LLC, a Quincy, Massachusetts-based company, is receiving $400,000 to revolutionize the drug manufacturing industry’s biopharmaceutical cell culture monitoring. The current state of cell culture maintenance necessitates close manual supervision. With the use of short-wave infrared hyperspectral imaging (SWIR-HSI), Applied Imaging Solutions is creating an AI-powered system that will enable contactless cell viability and metabolite level observation. Its goal is to increase the safety and efficiency of producing life-saving drugs by giving more accurate control over bioreactors.

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Improvements in Nano-Scale Simulations and Quantum Interconnects

NIST continues to prioritize quantum technology, as seen by the grant given to Boulder, Colorado-based Icarus Quantum Inc. A turnkey photon source based on semiconductor quantum dots was developed by the business with a $400,000 investment. This architecture, which combines several high-efficiency photon sources onto a single chip, is designed to scale. It is intended as a “plug-and-play” solution to facilitate the easier integration of quantum interconnects into researchers’ systems, therefore promoting the advancement of quantum computing and networking in general.

Software created by Schenectady, New York-based AMAG Consulting LLC complements these hardware advancements. With the help of a $400,000 grant, AMAG is improving its SimuSEM program, which models how electron beams interact with scanning electron microscope materials. The Phase II project includes surface roughness, magnetic interactions, and charging effects modeling. With these improvements, scientists will be able to produce more precise pictures at the nanoscale, which will lessen the need for expensive physical testing.

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Environmental Monitoring and Cybersecurity

Additionally, the SBIR program is tackling digital safety and the environment. A $395,814.74 grant will be given to Philadelphia-based MyExposome Inc. to enhance the functionality of wearable environmental sensors. To track a person’s exposure to per- and polyfluoroalkyl substances (PFAS), more often known as “forever chemicals,” the business employs silicone wristbands. To increase the range of PFAS that may be detected and offer an affordable instrument for environmental research and personal health evaluations, MyExposome is working to create innovative, solvent-free extraction methods.

To create the Operational Technology Artificial Intelligence – NIST Compliance Tool (OTAI-NCT), San Diego-based ObjectSecurity LLC obtained $399,908.58 in the digital space. This cybersecurity tool uses information from reliable sources, such as the National Vulnerability Database, to assess the policies of software and hardware vendors. A “cyber-hygiene score” is the final result, which gives customers the ability to make knowledgeable judgments about what to buy and eventually contributes to the protection of public safety and national security.

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Energy Efficiency and Optical Imaging Resolution

General imaging resolution and infrastructure initiatives complete the Phase II recipients. $400,000 was given to Harpers Ferry, West Virginia-based Universal Schedule and Booking LLC to create an intelligent digital infrastructure for home energy management. By estimating household energy usage without the need for costly hardware sensors, their approach overcomes a significant obstacle to the broad adoption of energy-saving technology.

The final award was $399,858.96 to HighRI Optics Inc. in Oakland, California, for the development of a binary pseudo-random array (BPRA) for optical image enhancement. With this invention, imaging systems utilized in scientific research, manufacturing, and military will have far higher resolution.

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Looking Forward

The eight initiatives showcase a wide range of the innovation economy in the United States. NIST supports small enterprises through the rigorous 24-month Phase II R&D cycle to develop technologies that might increase power grid resilience and cancer detection. As these firms reach milestones, they will strive to proceed to Phase III, where their discoveries can be commercialized.

What is the SBIR program?

SBIR (Small Business Innovation Research) is a U.S. government program that provides competitive funding (grants, contracts) to small businesses for research and development (R&D) of innovative technologies with commercial potential, acting as a major source of early-stage tech funding and fostering economic growth by linking small firms to federal R&D needs. Administered by 11 federal agencies, it’s often paired with STTR (Small Business Technology Transfer) and helps develop new products and processes while allowing businesses to retain equity, with funding typically in three phases: feasibility (Phase I), R&D/prototype (Phase II), and commercialization (Phase III).  

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